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The NFκB-inducing kinase is essential for the developmental programming of skin-resident and IL-17-producing γδ T cells

γδ T cells contribute to first line immune defense, particularly through their ability for rapid production of proinflammatory cytokines. The cytokine profile of γδ T cells is hard-wired already during thymic development. Yet, the molecular pathways underlying this phenomenon are incompletely unders...

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Detalles Bibliográficos
Autores principales: Mair, Florian, Joller, Stefanie, Hoeppli, Romy, Onder, Lucas, Hahn, Matthias, Ludewig, Burkhard, Waisman, Ari, Becher, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733042/
https://www.ncbi.nlm.nih.gov/pubmed/26637788
http://dx.doi.org/10.7554/eLife.10087