Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity

Heart of Glass (HEG1), a transmembrane receptor, and Rasip1, an endothelial-specific Rap1-binding protein, are both essential for cardiovascular development. Here we performed a proteomic screen for novel HEG1 interactors and report that HEG1 binds directly to Rasip1. Rasip1 localizes to forming end...

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Detalles Bibliográficos
Autores principales: de Kreuk, Bart-Jan, Gingras, Alexandre R, Knight, James DR, Liu, Jian J, Gingras, Anne-Claude, Ginsberg, Mark H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733052/
https://www.ncbi.nlm.nih.gov/pubmed/26780829
http://dx.doi.org/10.7554/eLife.11394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733052/
https://www.ncbi.nlm.nih.gov/pubmed/26780829
http://dx.doi.org/10.7554/eLife.11394

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