Cargando…

Role of complement in IgA nephropathy

Immunoglobulin A nephropathy (IgAN) is characterized by the deposition of IgA in the mesangium of glomeruli. This mesangial IgA has been found to consist mainly of polymeric IgA1 which drives the activation of the mesangial cells and results in excessive production of several inflammatory mediators....

Descripción completa

Detalles Bibliográficos
Autores principales: Daha, Mohamed R., van Kooten, Cees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733139/
https://www.ncbi.nlm.nih.gov/pubmed/26567162
http://dx.doi.org/10.1007/s40620-015-0245-6