pVAC-Seq: A genome-guided in silico approach to identifying tumor neoantigens

Cancer immunotherapy has gained significant momentum from recent clinical successes of checkpoint blockade inhibition. Massively parallel sequence analysis suggests a connection between mutational load and response to this class of therapy. Methods to identify which tumor-specific mutant peptides (n...

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Detalles Bibliográficos
Autores principales: Hundal, Jasreet, Carreno, Beatriz M., Petti, Allegra A., Linette, Gerald P., Griffith, Obi L., Mardis, Elaine R., Griffith, Malachi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733280/
https://www.ncbi.nlm.nih.gov/pubmed/26825632
http://dx.doi.org/10.1186/s13073-016-0264-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733280/
https://www.ncbi.nlm.nih.gov/pubmed/26825632
http://dx.doi.org/10.1186/s13073-016-0264-5

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