Cellular and molecular effects of metronomic vinorelbine and 4-O-deacetylvinorelbine on human umbilical vein endothelial cells

Metronomic oral vinorelbine (VRL; Navelbine) was shown in clinical trials to yield sustainable antitumor activity possibly through antiangiogenic mechanisms. We investigated the effects of protracted low-dose VRL on human umbilical vein endothelial cells, compared with a conventional chemotherapy mo...

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Detalles Bibliográficos
Autores principales: Biziota, Eirini, Briasoulis, Evangelos, Mavroeidis, Leonidas, Marselos, Marios, Harris, Adrian L., Pappas, Periklis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Preclinical Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733659/
https://www.ncbi.nlm.nih.gov/pubmed/26629767
http://dx.doi.org/10.1097/CAD.0000000000000319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733659/
https://www.ncbi.nlm.nih.gov/pubmed/26629767
http://dx.doi.org/10.1097/CAD.0000000000000319

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