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A multi-objective optimization approach accurately resolves protein domain architectures

Motivation: Given a protein sequence and a number of potential domains matching it, what are the domain content and the most likely domain architecture for the sequence? This problem is of fundamental importance in protein annotation, constituting one of the main steps of all predictive annotation s...

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Detalles Bibliográficos
Autores principales: Bernardes, J.S., Vieira, F.R.J., Zaverucha, G., Carbone, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734041/
https://www.ncbi.nlm.nih.gov/pubmed/26458889
http://dx.doi.org/10.1093/bioinformatics/btv582