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Resistance to the c-Met inhibitor KRC-108 induces the epithelial transition of gastric cancer cells

Investigation of the mechanisms of resistance to targeted therapies is essential as resistance acquired during treatment may lead to relapse or refractoriness to the therapy. Our previous study identified the small molecule KRC-108 as a result of efforts to find an anticancer agent with c-Met-inhibi...

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Detalles Bibliográficos
Autores principales: KIM, DONG CHUL, PARK, KYEONG RYANG, JEONG, YEON JI, YOON, HYONOK, AHN, MI-JEONG, RHO, GYU-JIN, LEE, JONGKOOK, GONG, YOUNG-DAE, HAN, SUN-YOUNG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734112/
https://www.ncbi.nlm.nih.gov/pubmed/26893681
http://dx.doi.org/10.3892/ol.2015.4029