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Broad and potent antiviral activity of the NAE inhibitor MLN4924

In terms of infected human individuals, herpesviruses range among the most successful virus families. Subclinical herpesviral infections in healthy individuals contrast with life-threatening syndromes under immunocompromising and immunoimmature conditions. Based on our finding that cytomegaloviruses...

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Detalles Bibliográficos
Autores principales: Le-Trilling, Vu Thuy Khanh, Megger, Dominik A., Katschinski, Benjamin, Landsberg, Christine D., Rückborn, Meike U., Tao, Sha, Krawczyk, Adalbert, Bayer, Wibke, Drexler, Ingo, Tenbusch, Matthias, Sitek, Barbara, Trilling, Mirko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734293/
https://www.ncbi.nlm.nih.gov/pubmed/26829401
http://dx.doi.org/10.1038/srep19977