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Synthesis of cyclic N(1)-pentylinosine phosphate, a new structurally reduced cADPR analogue with calcium-mobilizing activity on PC12 cells

Cyclic N(1)-pentylinosine monophosphate (cpIMP), a novel simplified inosine derivative of cyclic ADP-ribose (cADPR) in which the N(1)-pentyl chain and the monophosphate group replace the northern ribose and the pyrophosphate moieties, respectively, was synthesized. The role played by the position of...

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Detalles Bibliográficos
Autores principales: Mahal, Ahmed, D’Errico, Stefano, Borbone, Nicola, Pinto, Brunella, Secondo, Agnese, Costantino, Valeria, Tedeschi, Valentina, Oliviero, Giorgia, Piccialli, Vincenzo, Piccialli, Gennaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734301/
https://www.ncbi.nlm.nih.gov/pubmed/26877790
http://dx.doi.org/10.3762/bjoc.11.289