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Single-molecule mechanics of protein-labelled DNA handles

DNA handles are often used as spacers and linkers in single-molecule experiments to isolate and tether RNAs, proteins, enzymes and ribozymes, amongst other biomolecules, between surface-modified beads for nanomechanical investigations. Custom DNA handles with varying lengths and chemical end-modific...

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Detalles Bibliográficos
Autores principales: Jadhav, Vivek S, Brüggemann, Dorothea, Wruck, Florian, Hegner, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734302/
https://www.ncbi.nlm.nih.gov/pubmed/26925362
http://dx.doi.org/10.3762/bjnano.7.16