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Single-molecule mechanics of protein-labelled DNA handles
DNA handles are often used as spacers and linkers in single-molecule experiments to isolate and tether RNAs, proteins, enzymes and ribozymes, amongst other biomolecules, between surface-modified beads for nanomechanical investigations. Custom DNA handles with varying lengths and chemical end-modific...
Autores principales: | Jadhav, Vivek S, Brüggemann, Dorothea, Wruck, Florian, Hegner, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734302/ https://www.ncbi.nlm.nih.gov/pubmed/26925362 http://dx.doi.org/10.3762/bjnano.7.16 |
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