Structural characterisation of human galectin-4 N-terminal carbohydrate recognition domain in complex with glycerol, lactose, 3′-sulfo-lactose, and 2′-fucosyllactose

Galectin-4 is a tandem-repeat galectin with two distinct carbohydrate recognition domains (CRD). Galectin-4 is expressed mainly in the alimentary tract and is proposed to function as a lipid raft and adherens junction stabilizer by its glycan cross-linking capacity. Galectin-4 plays divergent roles...

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Detalles Bibliográficos
Autores principales: Bum-Erdene, Khuchtumur, Leffler, Hakon, Nilsson, Ulf J., Blanchard, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734333/
https://www.ncbi.nlm.nih.gov/pubmed/26828567
http://dx.doi.org/10.1038/srep20289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734333/
https://www.ncbi.nlm.nih.gov/pubmed/26828567
http://dx.doi.org/10.1038/srep20289

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