Enantioselective additions of copper acetylides to cyclic iminium and oxocarbenium ions

The development of enantioselective, copper-catalyzed alkynylations of cyclic iminium and oxocarbenium ions is reviewed. The use of chiral copper-based catalysts has enabled high yields and enantioselectivites in the formation of nitrogen- and oxygen-containing heterocycles with α-stereogenic center...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Jixin, Dasgupta, Srimoyee, Watson, Mary P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734405/
https://www.ncbi.nlm.nih.gov/pubmed/26877791
http://dx.doi.org/10.3762/bjoc.11.290
_version_ 1782412914912657408
author Liu, Jixin
Dasgupta, Srimoyee
Watson, Mary P
author_facet Liu, Jixin
Dasgupta, Srimoyee
Watson, Mary P
author_sort Liu, Jixin
collection PubMed
description The development of enantioselective, copper-catalyzed alkynylations of cyclic iminium and oxocarbenium ions is reviewed. The use of chiral copper-based catalysts has enabled high yields and enantioselectivites in the formation of nitrogen- and oxygen-containing heterocycles with α-stereogenic centers. This review highlights both the accomplishments and the future work needed in this important area.
format Online
Article
Text
id pubmed-4734405
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Beilstein-Institut
record_format MEDLINE/PubMed
spelling pubmed-47344052016-02-12 Enantioselective additions of copper acetylides to cyclic iminium and oxocarbenium ions Liu, Jixin Dasgupta, Srimoyee Watson, Mary P Beilstein J Org Chem Review The development of enantioselective, copper-catalyzed alkynylations of cyclic iminium and oxocarbenium ions is reviewed. The use of chiral copper-based catalysts has enabled high yields and enantioselectivites in the formation of nitrogen- and oxygen-containing heterocycles with α-stereogenic centers. This review highlights both the accomplishments and the future work needed in this important area. Beilstein-Institut 2015-12-22 /pmc/articles/PMC4734405/ /pubmed/26877791 http://dx.doi.org/10.3762/bjoc.11.290 Text en Copyright © 2015, Liu et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Review
Liu, Jixin
Dasgupta, Srimoyee
Watson, Mary P
Enantioselective additions of copper acetylides to cyclic iminium and oxocarbenium ions
title Enantioselective additions of copper acetylides to cyclic iminium and oxocarbenium ions
title_full Enantioselective additions of copper acetylides to cyclic iminium and oxocarbenium ions
title_fullStr Enantioselective additions of copper acetylides to cyclic iminium and oxocarbenium ions
title_full_unstemmed Enantioselective additions of copper acetylides to cyclic iminium and oxocarbenium ions
title_short Enantioselective additions of copper acetylides to cyclic iminium and oxocarbenium ions
title_sort enantioselective additions of copper acetylides to cyclic iminium and oxocarbenium ions
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734405/
https://www.ncbi.nlm.nih.gov/pubmed/26877791
http://dx.doi.org/10.3762/bjoc.11.290
work_keys_str_mv AT liujixin enantioselectiveadditionsofcopperacetylidestocycliciminiumandoxocarbeniumions
AT dasguptasrimoyee enantioselectiveadditionsofcopperacetylidestocycliciminiumandoxocarbeniumions
AT watsonmaryp enantioselectiveadditionsofcopperacetylidestocycliciminiumandoxocarbeniumions

Ejemplares similares