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pH-Triggered release from surface-modified poly(lactic-co-glycolic acid) nanoparticles

Nanoparticles (NP) of poly(lactic-co-glycolic acid) (PLGA) represent a promising biodegradable drug delivery system. We suggest here a two-step release system of PLGA nanoparticles with a pH-tunable polymeric shell, providing an initial pH-triggered step, releasing a membrane-toxic cationic compound...

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Detalles Bibliográficos
Autores principales: Häuser, Manuel, Langer, Klaus, Schönhoff, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734421/
https://www.ncbi.nlm.nih.gov/pubmed/26885463
http://dx.doi.org/10.3762/bjnano.6.260