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Epigenetic induction of epithelial to mesenchymal transition by LCN2 mediates metastasis and tumorigenesis, which is abrogated by NF-κB inhibitor BRM270 in a xenograft model of lung adenocarcinoma

Tumor initiating cancer stem-like cells (TICSCs) have recently become the object of intensive study. Human-Lipocalin-2 (hLCN2) acts as a biomarker for cancers. The aim of the present study was to explore new insights regarding the potential role of LCN2 in inducing epithelial to mesenchymal transiti...

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Detalles Bibliográficos
Autores principales: MONGRE, RAJ KUMAR, SODHI, SIMRINDER SINGH, SHARMA, NEELESH, GHOSH, MRINMOY, KIM, JEONG HYUN, KIM, NAMEUN, PARK, YANG HO, SHIN, YOUNG GYU, KIM, SUNG JIN, JIAO, ZHANG JIAO, HUYNH, DO LUONG, JEONG, DONG KEE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734607/
https://www.ncbi.nlm.nih.gov/pubmed/26573874
http://dx.doi.org/10.3892/ijo.2015.3245