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Decreased expression of RASSF1A tumor suppressor gene is associated with worse prognosis in clear cell renal cell carcinoma

Clear-cell renal cell carcinoma (ccRCC) is the most common subtype of RCC (70–80%) and is associated with poor prognosis in 40% of cases mainly due to metastasis in the course of the disease. RASSF1, with its isoforms RASSF1A and RASSF1C, is a tumor suppressor gene which has not been fully analyzed...

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Detalles Bibliográficos
Autores principales: KLACZ, JAKUB, WIERZBICKI, PIOTR M., WRONSKA, AGATA, RYBARCZYK, AGNIESZKA, STANISLAWOWSKI, MARCIN, SLEBIODA, TOMASZ, OLEJNICZAK, AGATA, MATUSZEWSKI, MARCIN, KMIEC, ZBIGNIEW
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734610/
https://www.ncbi.nlm.nih.gov/pubmed/26648328
http://dx.doi.org/10.3892/ijo.2015.3251