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MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit

GluN2A is the most abundant of the GluN2 NMDA receptor subunits in the mammalian CNS. Physiological and genetic evidence implicate GluN2A-containing receptors in susceptibility to autism, schizophrenia, childhood epilepsy and neurodevelopmental disorders such as Rett Syndrome. However, GluN2A-select...

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Detalles Bibliográficos
Autores principales: Volkmann, Robert A., Fanger, Christopher M., Anderson, David R., Sirivolu, Venkata Ramana, Paschetto, Kathy, Gordon, Earl, Virginio, Caterina, Gleyzes, Melanie, Buisson, Bruno, Steidl, Esther, Mierau, Susanna B., Fagiolini, Michela, Menniti, Frank S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734667/
https://www.ncbi.nlm.nih.gov/pubmed/26829109
http://dx.doi.org/10.1371/journal.pone.0148129