Hepatic Metastases is Associated with Poor Efficacy of Erlotinib as 2(nd)/3(rd) Line Therapy in Patients with Lung Adenocarcinoma

BACKGROUND: Hepatocyte growth factor (HGF)-mediated mesenchymal-to-epithelial transition factor (MET) gene amplification is a common mechanism for acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs). MET gene amplification has also been associated with hepa...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Yayi, Wang, Yan, Boyle, Theresa, Ren, Shengxiang, Chan, Dan, Rivard, Chris, Li, Xuefei, Li, Jiayu, Zhou, Caicun, Hirsch, Fred R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734673/
https://www.ncbi.nlm.nih.gov/pubmed/26811313
http://dx.doi.org/10.12659/MSM.896607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734673/
https://www.ncbi.nlm.nih.gov/pubmed/26811313
http://dx.doi.org/10.12659/MSM.896607

Ejemplares similares