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Automated Protein Localization of Blood Brain Barrier Vasculature in Brightfield IHC Images

In this paper, we present an objective method for localization of proteins in blood brain barrier (BBB) vasculature using standard immunohistochemistry (IHC) techniques and bright-field microscopy. Images from the hippocampal region at the BBB are acquired using bright-field microscopy and subjected...

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Detalles Bibliográficos
Autores principales: Soans, Rajath E., Lim, Diane C., Keenan, Brendan T., Pack, Allan I., Shackleford, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734698/
https://www.ncbi.nlm.nih.gov/pubmed/26828723
http://dx.doi.org/10.1371/journal.pone.0148411