Cargando…

Melanoma Expressed-CD70 Is Regulated by RhoA and MAPK Pathways without Affecting Vemurafenib Treatment Activity

CD70 is a costimulatory molecule member of the Tumor Necrosis Factor family that is expressed on activated immune cells. Its ectopic expression has been described in several types of cancer cells including lymphomas, renal cell carcinomas and glioblastomas. We have recently described its expression...

Descripción completa

Detalles Bibliográficos
Autores principales: Pich, Christine, Teiti, Iotefa, Sarrabayrouse, Guillaume, Gallardo, Franck, Gence, Rémi, Tilkin-Mariamé, Anne-Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734704/
https://www.ncbi.nlm.nih.gov/pubmed/26828592
http://dx.doi.org/10.1371/journal.pone.0148095