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Formulation, optimization, and pharmacodynamic evaluation of chitosan/phospholipid/β-cyclodextrin microspheres

Cholinergic neurotransmission loss is the main cause of cognitive impairment in patients with Alzheimer’s disease. Phospholipids (PLs) play an essential role in memory and learning abilities. Moreover, PLs act as a source of choline in acetylcholine synthesis. This study aimed to prepare and optimiz...

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Detalles Bibliográficos
Autores principales: Shan, Lu, Tao, En-Xue, Meng, Qing-Hui, Hou, Wen-Xia, Liu, Kang, Shang, Hong-Cai, Tang, Jin-Bao, Zhang, Wei-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734723/
https://www.ncbi.nlm.nih.gov/pubmed/26869763
http://dx.doi.org/10.2147/DDDT.S97982