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Decreased Bone Formation Explains Osteoporosis in a Genetic Mouse Model of Hemochromatosiss

Osteoporosis may complicate iron overload diseases such as genetic hemochromatosis. However, molecular mechanisms involved in the iron-related osteoporosis remains poorly understood. Recent in vitro studies support a role of osteoblast impairment in iron-related osteoporosis. Our aim was to analyse...

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Detalles Bibliográficos
Autores principales: Doyard, Mathilde, Chappard, Daniel, Leroyer, Patricia, Roth, Marie-Paule, Loréal, Olivier, Guggenbuhl, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734777/
https://www.ncbi.nlm.nih.gov/pubmed/26829642
http://dx.doi.org/10.1371/journal.pone.0148292