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Miconazole-loaded solid lipid nanoparticles: formulation and evaluation of a novel formula with high bioavailability and antifungal activity

BACKGROUND AND OBJECTIVE: Miconazole is a broad-spectrum antifungal drug that has poor aqueous solubility (<1 µg/mL); as a result, a reduction in its therapeutic efficacy has been reported. The aim of this study was to formulate and evaluate miconazole-loaded solid lipid nanoparticles (MN-SLNs) f...

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Detalles Bibliográficos
Autores principales: Aljaeid, Bader Mubarak, Hosny, Khaled Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734792/
https://www.ncbi.nlm.nih.gov/pubmed/26869787
http://dx.doi.org/10.2147/IJN.S100625