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Local delivery of controlled-release simvastatin to improve the biocompatibility of polyethylene terephthalate artificial ligaments for reconstruction of the anterior cruciate ligament

The Ligament Advanced Reinforcement System has recently been widely used as the primary graft of choice in anterior cruciate ligament (ACL) reconstruction. But the biological graft–bone healing still remains a problem. Previous studies have shown that simvastatin (SIM) stimulates bone formation. The...

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Detalles Bibliográficos
Autores principales: Zhang, Peng, Han, Fei, Li, Yunxia, Chen, Jiwu, Chen, Tianwu, Zhi, Yunlong, Jiang, Jia, Lin, Chao, Chen, Shiyi, Zhao, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734794/
https://www.ncbi.nlm.nih.gov/pubmed/26869789
http://dx.doi.org/10.2147/IJN.S95032