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Development of an Analysis Pipeline Characterizing Multiple Hypervariable Regions of 16S rRNA Using Mock Samples
OBJECTIVES: There is much speculation on which hypervariable region provides the highest bacterial specificity in 16S rRNA sequencing. The optimum solution to prevent bias and to obtain a comprehensive view of complex bacterial communities would be to sequence the entire 16S rRNA gene; however, this...
Autores principales: | Barb, Jennifer J., Oler, Andrew J., Kim, Hyung-Suk, Chalmers, Natalia, Wallen, Gwenyth R., Cashion, Ann, Munson, Peter J., Ames, Nancy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734828/ https://www.ncbi.nlm.nih.gov/pubmed/26829716 http://dx.doi.org/10.1371/journal.pone.0148047 |
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