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Inflammation-driven bone formation in a mouse model of ankylosing spondylitis: sequential not parallel processes

BACKGROUND: Ankylosing spondylitis (AS) is an immune-mediated arthritis particularly targeting the spine and pelvis and is characterised by inflammation, osteoproliferation and frequently ankylosis. Current treatments that predominately target inflammatory pathways have disappointing efficacy in slo...

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Detalles Bibliográficos
Autores principales: Tseng, Hsu-Wen, Pitt, Miranda E., Glant, Tibor T., McRae, Allan F., Kenna, Tony J., Brown, Matthew A., Pettit, Allison R., Thomas, Gethin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734853/
https://www.ncbi.nlm.nih.gov/pubmed/26831337
http://dx.doi.org/10.1186/s13075-015-0805-0