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External signals shape the epigenome

A new study shows how a single cytokine, interleukin-4, regulates hematopoietic lineage choice by activating the JAK3–STAT6 pathway, which causes dendritic-cell-specific DNA demethylation. Please see related Research article: http://www.genomebiology.com/2016/17/1/4

Detalles Bibliográficos
Autor principal: Lennartsson, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734871/
https://www.ncbi.nlm.nih.gov/pubmed/26829670
http://dx.doi.org/10.1186/s13059-016-0884-5