Cargando…
External signals shape the epigenome
A new study shows how a single cytokine, interleukin-4, regulates hematopoietic lineage choice by activating the JAK3–STAT6 pathway, which causes dendritic-cell-specific DNA demethylation. Please see related Research article: http://www.genomebiology.com/2016/17/1/4
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734871/ https://www.ncbi.nlm.nih.gov/pubmed/26829670 http://dx.doi.org/10.1186/s13059-016-0884-5 |
| Sumario: | A new study shows how a single cytokine, interleukin-4, regulates hematopoietic lineage choice by activating the JAK3–STAT6 pathway, which causes dendritic-cell-specific DNA demethylation. Please see related Research article: http://www.genomebiology.com/2016/17/1/4 |
|---|