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External signals shape the epigenome
A new study shows how a single cytokine, interleukin-4, regulates hematopoietic lineage choice by activating the JAK3–STAT6 pathway, which causes dendritic-cell-specific DNA demethylation. Please see related Research article: http://www.genomebiology.com/2016/17/1/4
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734871/ https://www.ncbi.nlm.nih.gov/pubmed/26829670 http://dx.doi.org/10.1186/s13059-016-0884-5 |
| _version_ | 1782412990163714048 |
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| author | Lennartsson, Andreas |
| author_facet | Lennartsson, Andreas |
| author_sort | Lennartsson, Andreas |
| collection | PubMed |
| description | A new study shows how a single cytokine, interleukin-4, regulates hematopoietic lineage choice by activating the JAK3–STAT6 pathway, which causes dendritic-cell-specific DNA demethylation. Please see related Research article: http://www.genomebiology.com/2016/17/1/4 |
| format | Online Article Text |
| id | pubmed-4734871 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2016 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-47348712016-02-02 External signals shape the epigenome Lennartsson, Andreas Genome Biol Research Highlight A new study shows how a single cytokine, interleukin-4, regulates hematopoietic lineage choice by activating the JAK3–STAT6 pathway, which causes dendritic-cell-specific DNA demethylation. Please see related Research article: http://www.genomebiology.com/2016/17/1/4 BioMed Central 2016-02-01 2016 /pmc/articles/PMC4734871/ /pubmed/26829670 http://dx.doi.org/10.1186/s13059-016-0884-5 Text en © Lennartsson. 2016 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| spellingShingle | Research Highlight Lennartsson, Andreas External signals shape the epigenome |
| title | External signals shape the epigenome |
| title_full | External signals shape the epigenome |
| title_fullStr | External signals shape the epigenome |
| title_full_unstemmed | External signals shape the epigenome |
| title_short | External signals shape the epigenome |
| title_sort | external signals shape the epigenome |
| topic | Research Highlight |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734871/ https://www.ncbi.nlm.nih.gov/pubmed/26829670 http://dx.doi.org/10.1186/s13059-016-0884-5 |
| work_keys_str_mv | AT lennartssonandreas externalsignalsshapetheepigenome |