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CIDANE: comprehensive isoform discovery and abundance estimation

We present CIDANE, a novel framework for genome-based transcript reconstruction and quantification from RNA-seq reads. CIDANE assembles transcripts efficiently with significantly higher sensitivity and precision than existing tools. Its algorithmic core not only reconstructs transcripts ab initio, b...

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Detalles Bibliográficos
Autores principales: Canzar, Stefan, Andreotti, Sandro, Weese, David, Reinert, Knut, Klau, Gunnar W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734886/
https://www.ncbi.nlm.nih.gov/pubmed/26831908
http://dx.doi.org/10.1186/s13059-015-0865-0