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CIDANE: comprehensive isoform discovery and abundance estimation

We present CIDANE, a novel framework for genome-based transcript reconstruction and quantification from RNA-seq reads. CIDANE assembles transcripts efficiently with significantly higher sensitivity and precision than existing tools. Its algorithmic core not only reconstructs transcripts ab initio, b...

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Detalles Bibliográficos
Autores principales:	Canzar, Stefan, Andreotti, Sandro, Weese, David, Reinert, Knut, Klau, Gunnar W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734886/ https://www.ncbi.nlm.nih.gov/pubmed/26831908 http://dx.doi.org/10.1186/s13059-015-0865-0

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