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Investigating the Consequences of Interference between Multiple CD8(+) T Cell Escape Mutations in Early HIV Infection

During early human immunodeficiency virus (HIV) infection multiple CD8(+) T cell responses are elicited almost simultaneously. These responses exert strong selective pressures on different parts of HIV’s genome, and select for mutations that escape recognition and are thus beneficial to the virus. S...

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Detalles Bibliográficos
Autores principales: Garcia, Victor, Feldman, Marcus W., Regoes, Roland R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735108/
https://www.ncbi.nlm.nih.gov/pubmed/26829720
http://dx.doi.org/10.1371/journal.pcbi.1004721