Oxidation of Phe454 in the Gating Segment Inactivates Trametes multicolor Pyranose Oxidase during Substrate Turnover

The flavin-dependent enzyme pyranose oxidase catalyses the oxidation of several pyranose sugars at position C-2. In a second reaction step, oxygen is reduced to hydrogen peroxide. POx is of interest for biocatalytic carbohydrate oxidations, yet it was found that the enzyme is rapidly inactivated und...

Descripción completa

Detalles Bibliográficos
Autores principales: Halada, Petr, Brugger, Dagmar, Volc, Jindrich, Peterbauer, Clemens K., Leitner, Christian, Haltrich, Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735113/
https://www.ncbi.nlm.nih.gov/pubmed/26828796
http://dx.doi.org/10.1371/journal.pone.0148108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735113/
https://www.ncbi.nlm.nih.gov/pubmed/26828796
http://dx.doi.org/10.1371/journal.pone.0148108

Ejemplares similares