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Oral Administration of Polymyxin B Modulates the Activity of Lipooligosaccharide E. coli B against Lung Metastases in Murine Tumor Models

INTRODUCTION: Polymyxin B (PmB) belongs to the group of cyclic peptide antibiotics, which neutralize the activity of LPS by binding to lipid A. The aim of this study was to analyze the effect of PmB on the biological activity of lipooligosaccharide (LOS E. coli B,rough form of LPS) in vitro and in e...

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Detalles Bibliográficos
Autores principales: Kicielińska, Jagoda, Szczygieł, Agnieszka, Rossowska, Joanna, Anger, Natalia, Kempińska, Katarzyna, Świtalska, Marta, Kaszowska, Marta, Wietrzyk, Joanna, Boratyński, Janusz, Pajtasz-Piasecka, Elżbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735115/
https://www.ncbi.nlm.nih.gov/pubmed/26829479
http://dx.doi.org/10.1371/journal.pone.0148156