mTOR masters monocytic myeloid-derived suppressor cells in mice with allografts or tumors

CD11b(+) Gr1(+) myeloid-derived suppressor cells (MDSCs) play critical roles in controlling the processes of tumors, infections, autoimmunity and graft rejection. Immunosuppressive drug rapamycin (RPM), targeting on the key cellular metabolism molecule mTOR, is currently used in clinics to treat pat...

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Detalles Bibliográficos
Autores principales: Wu, Tingting, Zhao, Yang, Wang, Hao, Li, yang, Shao, Lijuan, Wang, Ruoyu, Lu, Jun, Yang, Zhongzhou, Wang, Junjie, Zhao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735296/
https://www.ncbi.nlm.nih.gov/pubmed/26833095
http://dx.doi.org/10.1038/srep20250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735296/
https://www.ncbi.nlm.nih.gov/pubmed/26833095
http://dx.doi.org/10.1038/srep20250

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