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ATTIRE: Albumin To prevenT Infection in chronic liveR failurE: study protocol for a single-arm feasibility trial

INTRODUCTION: Circulating prostaglandin E(2) levels are elevated in acutely decompensated cirrhosis and have been shown to contribute to immune suppression. Albumin binds and inactivates this hormone. Human albumin solution could thus be repurposed as an immune restorative drug in these patients. Th...

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Detalles Bibliográficos
Autores principales: China, Louise, Muirhead, Nicola, Skene, Simon S, Shabir, Zainib, PH De Maeyer, Roel, Maini, Alexander AN, W Gilroy, Derek, J O'Brien, Alastair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735307/
https://www.ncbi.nlm.nih.gov/pubmed/26810999
http://dx.doi.org/10.1136/bmjopen-2015-010132