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Heart Rate and Extracellular Sodium and Potassium Modulation of Gap Junction Mediated Conduction in Guinea Pigs

Background: Recent studies suggested that cardiac conduction in murine hearts with narrow perinexi and 50% reduced connexin43 (Cx43) expression is more sensitive to relatively physiological changes of extracellular potassium ([K(+)](o)) and sodium ([Na(+)](o)). Purpose: Determine whether similar [K(...

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Detalles Bibliográficos
Autores principales: Entz, Michael, George, Sharon A., Zeitz, Michael J., Raisch, Tristan, Smyth, James W., Poelzing, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735342/
https://www.ncbi.nlm.nih.gov/pubmed/26869934
http://dx.doi.org/10.3389/fphys.2016.00016