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Overexpression of Isoforms of Nitric Oxide Synthase 1 Adaptor Protein, Encoded by a Risk Gene for Schizophrenia, Alters Actin Dynamics and Synaptic Function

Proper communication between neurons depends upon appropriate patterning of dendrites and correct distribution and structure of spines. Schizophrenia is a neuropsychiatric disorder characterized by alterations in dendrite branching and spine density. Nitric oxide synthase 1 adaptor protein (NOS1AP),...

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Detalles Bibliográficos
Autores principales: Hernandez, Kristina, Swiatkowski, Przemyslaw, Patel, Mihir V., Liang, Chen, Dudzinski, Natasha R., Brzustowicz, Linda M., Firestein, Bonnie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735351/
https://www.ncbi.nlm.nih.gov/pubmed/26869880
http://dx.doi.org/10.3389/fncel.2016.00006