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A Toolkit for Orthogonal and in vivo Optical Manipulation of Ionotropic Glutamate Receptors
The ability to optically manipulate specific neuronal signaling proteins with genetic precision paves the way for the dissection of their roles in brain function, behavior, and disease. Chemical optogenetic control with photoswitchable tethered ligands (PTLs) enables rapid, reversible and reproducib...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735401/ https://www.ncbi.nlm.nih.gov/pubmed/26869877 http://dx.doi.org/10.3389/fnmol.2016.00002 |