Cargando…

A Toolkit for Orthogonal and in vivo Optical Manipulation of Ionotropic Glutamate Receptors

The ability to optically manipulate specific neuronal signaling proteins with genetic precision paves the way for the dissection of their roles in brain function, behavior, and disease. Chemical optogenetic control with photoswitchable tethered ligands (PTLs) enables rapid, reversible and reproducib...

Descripción completa

Detalles Bibliográficos
Autores principales:	Levitz, Joshua, Popescu, Andrei T., Reiner, Andreas, Isacoff, Ehud Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735401/ https://www.ncbi.nlm.nih.gov/pubmed/26869877 http://dx.doi.org/10.3389/fnmol.2016.00002

Ejemplares similares

Optical Control of Metabotropic Glutamate Receptors
por: Levitz, Joshua, et al.
Publicado: (2013)

Ubiquitin-dependent trafficking and turnover of ionotropic glutamate receptors
por: Goo, Marisa S., et al.
Publicado: (2015)

Editorial: Ionotropic Glutamate Receptors Trafficking in Health and Disease
por: Petrovic, Milos, et al.
Publicado: (2016)

Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand
por: Broichhagen, Johannes, et al.
Publicado: (2015)

Synergism of type 1 metabotropic and ionotropic glutamate receptors in cerebellar molecular layer interneurons in vivo
por: Bao, Jin, et al.
Publicado: (2020)

Undifferentiated embryonic stem cells express ionotropic glutamate receptor mRNAs
por: Pachernegg, Svenja, et al.
Publicado: (2013)

Tethered ligands reveal glutamate receptor desensitization depends on subunit occupancy
por: Reiner, Andreas, et al.
Publicado: (2014)

Distinct combinations of variant ionotropic glutamate receptors mediate thermosensation and hygrosensation in Drosophila
por: Knecht, Zachary A, et al.
Publicado: (2016)

Expression of specific ionotropic glutamate and GABA-A receptor subunits is decreased in central amygdala of alcoholics
por: Jin, Zhe, et al.
Publicado: (2014)

Structural Mechanisms of Gating in Ionotropic Glutamate Receptors
por: Twomey, Edward C., et al.
Publicado: (2017)

Targeting Ionotropic Glutamate Receptors in the Treatment of Epilepsy
por: Celli, Roberta, et al.
Publicado: (2021)

Pathophysiological Ionotropic Glutamate Signalling in Neuroinflammatory Disease as a Therapeutic Target
por: Fairless, Richard, et al.
Publicado: (2021)

Phosphoproteomic Alterations of Ionotropic Glutamate Receptors in the Hippocampus of the Ts65Dn Mouse Model of Down Syndrome
por: Gómez de Salazar, Macarena, et al.
Publicado: (2018)

Synaptic NR2A- but not NR2B-Containing NMDA Receptors Increase with Blockade of Ionotropic Glutamate Receptors
por: von Engelhardt, Jakob, et al.
Publicado: (2009)

Splicing and editing of ionotropic glutamate receptors: a comprehensive analysis based on human RNA-Seq data
por: Herbrechter, Robin, et al.
Publicado: (2021)

The Structure and Function of Ionotropic Receptors in Drosophila
por: Ni, Lina
Publicado: (2021)

Conformational dynamics of a class C G protein-coupled receptor
por: Vafabakhsh, Reza, et al.
Publicado: (2015)

Glutamate triggers the expression of functional ionotropic and metabotropic glutamate receptors in mast cells
por: Alim, Md Abdul, et al.
Publicado: (2020)

Ionotropic Glutamate Receptor AMPA 1 Is Associated with Ovulation Rate
por: Sugimoto, Mayumi, et al.
Publicado: (2010)

Diabetes changes the levels of ionotropic glutamate receptors in the rat retina
por: Santiago, Ana R., et al.
Publicado: (2009)

Expression of ionotropic glutamate receptors in the retina of the rdta transgenic mouse
por: Liu, Ling O, et al.
Publicado: (2001)

Computational Study of Synthetic Agonist Ligands of Ionotropic Glutamate Receptors
por: Wolter, Tino, et al.
Publicado: (2013)

Probing Intersubunit Interfaces in AMPA-subtype Ionotropic Glutamate Receptors
por: Yelshanskaya, Maria V., et al.
Publicado: (2016)

Developmental and Activity Dependent Regulation of Ionotropic Glutamate Receptors at Synapses
por: Molnar, Elek, et al.
Publicado: (2002)

The Reactive Plasticity of Hippocampal Ionotropic Glutamate Receptors in Animal Epilepsies
por: Mihály, András
Publicado: (2019)

Role of actin cytoskeleton in the organization and function of ionotropic glutamate receptors
por: Dutta, Priyanka, et al.
Publicado: (2021)

A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing
por: Janovjak, Harald, et al.
Publicado: (2010)

Correction to: Glutamate triggers the expression of functional ionotropic and metabotropic glutamate receptors in mast cells
por: Alim, Md Abdul, et al.
Publicado: (2020)

Ionotropic Glutamate Receptors in Epilepsy: A Review Focusing on AMPA and NMDA Receptors
por: Hanada, Takahisa
Publicado: (2020)

Involvement of peripheral ionotropic glutamate receptors in orofacial thermal hyperalgesia in rats
por: Honda, Kuniya, et al.
Publicado: (2011)

Correction: Computational Study of Synthetic Agonist Ligands of Ionotropic Glutamate Receptors
por: Wolter, Tino, et al.
Publicado: (2014)

The utility of ionotropic glutamate receptor antagonists in the treatment of nociception induced by epidural glutamate infusion in rats
por: Osgood, Doreen P., et al.
Publicado: (2013)

In vivo assembly and trafficking of olfactory Ionotropic Receptors
por: Abuin, Liliane, et al.
Publicado: (2019)

Separate Ionotropic and Metabotropic Glutamate Receptor Functions in Depotentiation vs. LTP: A Distinct Role for Group1 mGluR Subtypes and NMDARs
por: Latif-Hernandez, Amira, et al.
Publicado: (2016)

Modulation of Ionotropic Glutamate Receptors and Acid-Sensing Ion Channels by Nitric Oxide
por: Wang, John Q., et al.
Publicado: (2012)

Ionotropic Glutamate Receptors Mediate Inducible Defense in the Water Flea Daphnia pulex
por: Miyakawa, Hitoshi, et al.
Publicado: (2015)

Structure, Dynamics, and Allosteric Potential of Ionotropic Glutamate Receptor N-Terminal Domains
por: Krieger, James, et al.
Publicado: (2015)

Activation and desensitization of ionotropic glutamate receptors by selectively triggering pre-existing motions
por: Krieger, James, et al.
Publicado: (2019)

Expression of ionotropic receptors in terrestrial hermit crab's olfactory sensory neurons
por: Groh-Lunow, Katrin C., et al.
Publicado: (2015)

Ionotropic Receptor-dependent moist and dry cells control hygrosensation in Drosophila
por: Knecht, Zachary A, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_1as4cp5fi5n42slmdo7mdooqte