A Conserved HIV-1-Derived Peptide Presented by HLA-E Renders Infected T-cells Highly Susceptible to Attack by NKG2A/CD94-Bearing Natural Killer Cells

Major histocompatibility class I (MHC-I)-specific inhibitory receptors on natural killer (NK) cells (iNKRs) tolerize mature NK cell responses toward normal cells. NK cells generate cytolytic responses to virus-infected or malignant target cells with altered or decreased MHC-I surface expression due...

Descripción completa

Detalles Bibliográficos
Autores principales: Davis, Zachary B., Cogswell, Andrew, Scott, Hamish, Mertsching, Amanda, Boucau, Julie, Wambua, Daniel, Le Gall, Sylvie, Planelles, Vicente, Campbell, Kerry S., Barker, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735451/
https://www.ncbi.nlm.nih.gov/pubmed/26828202
http://dx.doi.org/10.1371/journal.ppat.1005421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735451/
https://www.ncbi.nlm.nih.gov/pubmed/26828202
http://dx.doi.org/10.1371/journal.ppat.1005421

Ejemplares similares