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NSAIDs attenuate hyperalgesia induced by TRP channel activation

Transient receptor potential (TRP) cation channels have been extensively investigated as targets for analgesic drug discovery. Because some non-steroidal anti-inflammatory drugs (NSAIDs) are structural analogs of prostaglandins (mediators of inflammation) and NSAIDs attenuate heat nociception and me...

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Detalles Bibliográficos
Autores principales: Nozadze, Ivliane, Tsiklauri, Nana, Gurtskaia, Gulnaz, Tsagareli, Merab G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735497/
https://www.ncbi.nlm.nih.gov/pubmed/26909384
http://dx.doi.org/10.1016/j.dib.2015.12.055