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Chromatin topology is coupled to Polycomb group protein subnuclear organization

The genomes of metazoa are organized at multiple scales. Many proteins that regulate genome architecture, including Polycomb group (PcG) proteins, form subnuclear structures. Deciphering mechanistic links between protein organization and chromatin architecture requires precise description and mechan...

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Detalles Bibliográficos
Autores principales: Wani, Ajazul H., Boettiger, Alistair N., Schorderet, Patrick, Ergun, Ayla, Münger, Christine, Sadreyev, Ruslan I., Zhuang, Xiaowei, Kingston, Robert E., Francis, Nicole J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735512/
https://www.ncbi.nlm.nih.gov/pubmed/26759081
http://dx.doi.org/10.1038/ncomms10291