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Proteome-wide survey of the autoimmune target repertoire in autoimmune polyendocrine syndrome type 1

Autoimmune polyendocrine syndrome type 1 (APS1) is a monogenic disorder that features multiple autoimmune disease manifestations. It is caused by mutations in the Autoimmune regulator (AIRE) gene, which promote thymic display of thousands of peripheral tissue antigens in a process critical for estab...

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Detalles Bibliográficos
Autores principales: Landegren, Nils, Sharon, Donald, Freyhult, Eva, Hallgren, Åsa, Eriksson, Daniel, Edqvist, Per-Henrik, Bensing, Sophie, Wahlberg, Jeanette, Nelson, Lawrence M., Gustafsson, Jan, Husebye, Eystein S., Anderson, Mark S., Snyder, Michael, Kämpe, Olle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735587/
https://www.ncbi.nlm.nih.gov/pubmed/26830021
http://dx.doi.org/10.1038/srep20104