Combined local and systemic immunization is essential for durable T-cell mediated heterosubtypic immunity against influenza A virus

The threat from unpredictable influenza virus pandemics necessitates the development of a new type of influenza vaccine. Since the internal proteins are highly conserved, induction of T cells targeting these antigens may provide the solution. Indeed, adenoviral (Ad) vectors expressing flu nucleoprot...

Descripción completa

Detalles Bibliográficos
Autores principales: Uddback, Ida E. M., Pedersen, Line M. I., Pedersen, Sara R., Steffensen, Maria A., Holst, Peter J., Thomsen, Allan R., Christensen, Jan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735591/
https://www.ncbi.nlm.nih.gov/pubmed/26831578
http://dx.doi.org/10.1038/srep20137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735591/
https://www.ncbi.nlm.nih.gov/pubmed/26831578
http://dx.doi.org/10.1038/srep20137

Ejemplares similares