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Phenanthrene exposure induces cardiac hypertrophy via reducing miR-133a expression by DNA methylation

Growing evidence indicates that there is an emerging link between environmental pollution and cardiac hypertrophy, while the mechanism is unclear. The objective of this study was to examine whether phenanthrene (Phe) could cause cardiac hypertrophy, and elucidate the molecular mechanisms involved. W...

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Detalles Bibliográficos
Autores principales: Huang, Lixing, Xi, Zhihui, Wang, Chonggang, Zhang, Youyu, Yang, Zhibing, Zhang, Shiqi, Chen, Yixin, Zuo, Zhenghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735597/
https://www.ncbi.nlm.nih.gov/pubmed/26830171
http://dx.doi.org/10.1038/srep20105