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Functional anterior pituitary generated in self-organizing culture of human embryonic stem cells

Anterior pituitary is critical for endocrine systems. Its hormonal responses to positive and negative regulators are indispensable for homeostasis. For this reason, generating human anterior pituitary tissue that retains regulatory hormonal control in vitro is an important step for the development o...

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Detalles Bibliográficos
Autores principales: Ozone, Chikafumi, Suga, Hidetaka, Eiraku, Mototsugu, Kadoshima, Taisuke, Yonemura, Shigenobu, Takata, Nozomu, Oiso, Yutaka, Tsuji, Takashi, Sasai, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735598/
https://www.ncbi.nlm.nih.gov/pubmed/26762480
http://dx.doi.org/10.1038/ncomms10351