Targeting of CCL2-CCR2-Glycosaminoglycan Axis Using a CCL2 Decoy Protein Attenuates Metastasis through Inhibition of Tumor Cell Seeding()

The CCL2-CCR2 chemokine axis has an important role in cancer progression where it contributes to metastatic dissemination of several cancer types (e.g., colon, breast, prostate). Tumor cell–derived CCL2 was shown to promote the recruitment of CCR2(+)/Ly6C(hi) monocytes and to induce vascular permeab...

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Detalles Bibliográficos
Autores principales: Roblek, Marko, Strutzmann, Elisabeth, Zankl, Christina, Adage, Tiziana, Heikenwalder, Mathias, Atlic, Aid, Weis, Roland, Kungl, Andreas, Borsig, Lubor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735630/
https://www.ncbi.nlm.nih.gov/pubmed/26806351
http://dx.doi.org/10.1016/j.neo.2015.11.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735630/
https://www.ncbi.nlm.nih.gov/pubmed/26806351
http://dx.doi.org/10.1016/j.neo.2015.11.013

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