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Native characterization of nucleic acid motif thermodynamics via non-covalent catalysis

DNA hybridization thermodynamics is critical for accurate design of oligonucleotides for biotechnology and nanotechnology applications, but parameters currently in use are inaccurately extrapolated based on limited quantitative understanding of thermal behaviours. Here, we present a method to measur...

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Detalles Bibliográficos
Autores principales: Wang, Chunyan, Bae, Jin H., Zhang, David Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735651/
https://www.ncbi.nlm.nih.gov/pubmed/26782977
http://dx.doi.org/10.1038/ncomms10319