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Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia

OBJECTIVES: Cancer cachexia affects the majority of tumor patients and significantly contributes to high mortality rates in these subjects. Despite its clinical importance, the identity of tumor-borne signals and their impact on specific peripheral organ systems, particularly the heart, remain mostl...

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Detalles Bibliográficos
Autores principales: Schäfer, Michaela, Oeing, Christian U., Rohm, Maria, Baysal-Temel, Ezgi, Lehmann, Lorenz H., Bauer, Ralf, Volz, H. Christian, Boutros, Michael, Sohn, Daniela, Sticht, Carsten, Gretz, Norbert, Eichelbaum, Katrin, Werner, Tessa, Hirt, Marc N., Eschenhagen, Thomas, Müller-Decker, Karin, Strobel, Oliver, Hackert, Thilo, Krijgsveld, Jeroen, Katus, Hugo A., Berriel Diaz, Mauricio, Backs, Johannes, Herzig, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735665/
https://www.ncbi.nlm.nih.gov/pubmed/26909315
http://dx.doi.org/10.1016/j.molmet.2015.11.004